Eph receptors tangled up in two: Independent control of cell positioning and proliferation

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Eph Receptors: Two Ways to Sharpen Boundaries

Eph receptors and ephrins can sharpen domains within developing tissues by mediating repulsion at interfaces. An Eph receptor has now been shown also to regulate cell adhesion within tissue subdivisions.

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Tangled (up in) cubes.

The 'simplest' entanglements of the graph of edges of the cube are enumerated, forming two-cell {6, 3} (hexagonal mesh) complexes on the genus-one two-dimensional torus. Five chiral pairs of knotted graphs are found. The examples contain non-trivial knotted and/or linked subgraphs [(2, 2), (2, 4) torus links and (3, 2), (4, 3) torus knots].

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Ephrins and Eph Receptors

chemorepulsive factors. Integrin heterodimers are primary ECM receptors, which can exist in different functional states with respect to their affinity or avidity for ECM proteins (11, 35), and directed cell motility on ECM is promoted by targeted localization of high-affinity integrins at the leading edge of migrating cells (40). There is now mounting evidence that both chemoattractant and chem...

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ژورنال

عنوان ژورنال: Cell Cycle

سال: 2010

ISSN: 1538-4101,1551-4005

DOI: 10.4161/cc.9.10.11677